发明名称 POLYAMINE THIOLS AS RADIOPROTECTIVE AGENTS
摘要 The present invention relates to certain polyamine thiols of the formula (1) or (2) <See formula I> <See formula II> wherein n is an integer from 0 to 3, m is an integer from 4 to 9, Z is a C2-C6 alkylene group, A is H, -SH, -SPO3H2, -N(CH2)q-SH, -N(CH2)q-SPO3H2, wherein q is an integer 2 to 4, and B1 and B2 are each independently H, -(CH2)q-SH, or -(CH2)q-SPO3H2. with the proviso that at least one of A, B1 and B2 is other than H, which are useful as radioprotective agents.
申请公布号 CA2059817(A1) 申请公布日期 1992.07.24
申请号 CA19922059817 申请日期 1992.01.22
申请人 MERRELL DOW PHARMA 发明人 EDWARDS MICHAEL L;SNYDER RONALD D
分类号 A61K31/135;A61K31/66;A61P39/02;A61P43/00;C07C319/08;C07C319/12;C07C323/25;C07C323/32;C07C323/34;C07F9/165;C07F9/18;(IPC1-7):C07C323/31 主分类号 A61K31/135
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