发明名称 |
9-HALOGEN-11(BETA)-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT |
摘要 |
The invention relates to 9-halogen-11.beta.-hydroxy-prostane derivatives of formula I (I), in which Z means the radicals or , Hal means an .alpha.- or .beta.-position chlorine or fluorine atom, R1 means the radical CH2OH or with R2 meaning a hydrogen atom, an alkyl, cycloalkyl, aryl or heterocyclic radical or R1 means the radical with R3 meaning an acid radical or radical R2 and R4 means a cycloalkyl group, and if R2 has the meaning of a hydrogen atom, its salts with physiologically compatible bases and its cyclodextrin clathrates, process for their production and their pharmaceutical use. |
申请公布号 |
WO9208697(A3) |
申请公布日期 |
1992.07.23 |
申请号 |
WO1991DE00881 |
申请日期 |
1991.11.08 |
申请人 |
SCHERING AKTIENGESELLSCHAFT, BERLIN UND BERGKAMEN |
发明人 |
BUCHMANN, BERND;SKUBALLA, WERNER;THIERAUCH, KARL-HEINZ;VERHALLEN, PETER |
分类号 |
A61K31/557;A61K31/5575;A61P1/00;A61P1/04;C07C405/00 |
主分类号 |
A61K31/557 |
代理机构 |
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代理人 |
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地址 |
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