摘要 |
<p>PCT No. PCT/US84/00525 Sec. 371 Date Nov. 22, 1985 Sec. 102(e) Date Nov. 22, 1985 PCT Filed Apr. 6, 1984 PCT Pub. No. WO85/04663 PCT Pub. Date Oct. 24, 1985.A process for detecting specific nucleotide sequences, called targets, in which a special DNA probe molecule, called a probe-vector, is capable of transforming bacteria if and only if it is held in a circular configuration by base pairing to a target nucleic acid, said transformation resulting in the detection of a phenotype specified by the probe-vector, said detection establishing the presence, absence, or quantity of the target; and a probe-vector molecule for performing the process.</p> |