发明名称 HEPATOPATHY-TREATING MEDICINE
摘要 <p>NEW MATERIAL:A compound of formula I (X is O, CH2, (n) is 1, 2). EXAMPLE:5-(3-Methoxy-4-hydroxyphenyl)-2,4-pentadienic acid prenyl ester. USE:A hepatopathy-treating agent. PREPARATION:A carboxylic acid derivative of formula II is condensed with an isoprenyl alcohol of formula III ((m) is 1, 2) and subsequently subjected to a protecting group-removing reaction to provide the compound of formula I. Or, an aldehyde derivative of formula IV and isoprenyl acetone of formula V ((p) is 1, 2) are subjected to aldol reaction and subsequently to a dehydration reaction and a protecting group-removing reaction to provide the compound of formula I.</p>
申请公布号 JPH04202133(A) 申请公布日期 1992.07.22
申请号 JP19900329578 申请日期 1990.11.30
申请人 TERUMO CORP 发明人 KUBO AKIHIRO;ONISHI HIROYUKI;MIYAOKA SHOZO;NANBA RYOICHI;SHIMIZU MASAKI
分类号 A61K31/12;A61K31/22;A61P1/16;A61P31/12;C07C49/255;C07C69/734 主分类号 A61K31/12
代理机构 代理人
主权项
地址