Hexa-cyclic compound.

摘要

A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.