DERIVATIZED TRIS-CATECHOL CHELATING AGENTS

摘要

Bifunctional chelating agents are designed to sequester certain radioactive metals, such as gallium (III) isotopes, and to provide a means for covalently attaching these radionuclides to macromolecules, such as monoclonal antibodies. These chelating agents may be used in various therapeutic and diagnostic methods, such as in radioimaging and positron emission tomography.