This invention relates to compounds of structural formula (I): <IMAGE> (I) (CH2)4CHCH(CH2)4CHCHCH3 which are squalene synthetase inhibitors and thus useful as cholesterol lowering agents.
申请公布号
US5132320(A)
申请公布日期
1992.07.21
申请号
US19900496734
申请日期
1990.03.21
申请人
MERCK & CO., INC.
发明人
BERGSTROM, JAMES D.;HENSENS, OTTO D.;DUFRESNE, CLAUDE;HUANG, LEEYUAN;ONISHI, JANET C.;ZINK, DEBORAH L.