发明名称 |
METHOD FOR INHIBITING PRODUCTION OF IGE AND METHOD FOR ENHANCING PRODUCTION OF IGG USING INTERLEUKIN 9 AND INHIBITORS THEREOF |
摘要 |
A method for inhibiting production of IgE, and a method for enhancing production of IgG are taught. The methods are linked to the role of interleukin 9 in antibody production. Specifically, production of IgG is potentiated by administering either to a subject or a cell culture a combination of interleukin 4 and interleukin 9. Production of IgE is inhibited by administering an amount of an interleukin 9 inhibitor to a subject.
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申请公布号 |
US5132109(A) |
申请公布日期 |
1992.07.21 |
申请号 |
US19900593238 |
申请日期 |
1990.10.05 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH;DEPARTEMENTE D'IMMUNOLOGIE INSTITUT HENRI BEAUFOUR |
发明人 |
DUGAS, BERNARD;DRUEZ, CATHERINE;BRAQUET, PIERRE;MENCIA-HUERTA, JEAN M.;UYTTENHOVE, CATHERINE;RENAULD, JEAN-CHRISTOPHE;VAN SNICK, JACQUES |
分类号 |
A61K38/00;A61K38/17;A61K38/20;A61K39/395;A61K45/00;A61P37/00;A61P37/04;A61P37/06;A61P43/00;C07K14/54;C07K14/715;C07K16/24;C12N5/08;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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