Ocular implants and methods for their manufacture

摘要

A method for modifying an ocular implant polymer surface by the gamma-irradiation or electron beam irradiation induced polymerization thereon of N-vinylpyrrolidone, 2-hydroxyethylmethacrylate or a mixture thereof while maintaining the following conditions: (a) monomer concentration in the range of from about 0.1% to about 50%, by weight; (b) total gamma dose in the range of from about 0.001 to less than about 0.50 Mrad; and (c) gamma dose rate in the range of from about 10 to about 2500 rads/minute or electron beam irradiation dose rate in the range of from about 10 to about 108 rads/minute.