| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I [R<1> us H or organic group removable in an acidic, an alkaline or a reductive manner; R<2> is H or carboxyl-protecting group) in which the steric configuration at its 5-position is (R) configuration]. EXAMPLE:A compound expressed by formula II. USE:An intermediate for producing various medicines such as beta--lactam-based antibiotic substances having antimicrobial activity. PREPARATION:A carbapenem derivative expressed by formula III in which its 5-position is (R) configuration is converted into a diol using osmium tetroxide.</p> |
