METHOD FOR IMMOBILIZATION OF THIOL COMPOUNDS VIA ACTIVATION OF POLYMERS, ACTIVATED POLYMERS, AND PRODUCTS OBTAINED BY THE METHOD

摘要

Method for the immobilization of an organic thiol compound, HS-R, to a polymer exhibiting a disulfide (-S-S-) group directly bound to a saturated carbon atom at each of its sulfur atoms. The method is characterized by the steps that (i) said polymer is contacted with an oxidation agent transforming said disulfide (-S-S-) group to an oxidized disulfide group, preferably a -S-SOn- group where n is 1 or 2, whereupon (ii) the polymer is contacted with the organic thiol compound HS-R to the formation of one -S-S-R group and one -SOn(H) group per disulfide oxide group that undergoes the reaction. Insoluble support (polymer) exhibiting a -S-SOn- group attached directly to a saturated carbon atom at each of its sulfur atoms and n=1 or 2. Polymer carrying equimolar amounts of -S-S-R and -SOn(H) groups bound directly to a respective saturated carbon atom in the polymer, where R is an organic residue providing a carbon atom attached directly at the sulfur atom and n being 1 or 2. Wool textile fibres are excluded as the polymer.