发明名称 |
POLYAMINE DRUG-RESIN COMPLEXES |
摘要 |
Disclosed are oral pharmaceutical preparations which comprise a pharmacologically-active polyamine drug bound to a cation-exchange resin to provide a drug-resin complex having a drug content greater than one equivalent of amine per equivalent of cation-exchange capacity. The drug-resin complex is optionally coated with a water-permeable diffusion barrier coating that is insoluble in gastrointestinal fluids thereby providing a controllable release of drug under conditions encountered in the gastrointestinal tract. |
申请公布号 |
WO9211038(A1) |
申请公布日期 |
1992.07.09 |
申请号 |
WO1991US09463 |
申请日期 |
1991.12.16 |
申请人 |
RICHARDSON-VICKS INC. |
发明人 |
KELLEHER, WILLIAM, JOSEPH;CARPANZANO, ANTHONY, EARL |
分类号 |
A61K47/00;A61K47/48 |
主分类号 |
A61K47/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|