发明名称 ANTI-INFLAMMATORY COMPOUNDS
摘要 This invention encompasses compounds of formula (I) and the stereoisomers and pharmaceutically acceptable salts thereof. In formula (I) R represents lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, or -(CH2)m-R<3> wherein R<3> represents cycloalkyl of 3 to 5 carbon atoms and m is 1, 2 or 3; R1 is -CONH2 or alpha wherein R2 is lower alkyl, phenyl, unsubstituted or substituted with loweralkyl, or beta ; and n is an integer from 2 to 5. The compounds are useful anti-inflammatory agents for treating, for example, inflammatory bowel disease, rheumatoid arthritis, gout, asthma and psoriasis.
申请公布号 WO9211252(A1) 申请公布日期 1992.07.09
申请号 WO1991US09126 申请日期 1991.12.11
申请人 G.D. SEARLE & CO. 发明人 DJURIC, STEVAN, WAKEFIELD;FRETLAND, DONALD, JOHN;YU, STELLA, SIU-TZYY
分类号 C07D311/66;C07D405/12 主分类号 C07D311/66
代理机构 代理人
主权项
地址