发明名称 FLAVOR STABLE ZINC ACETATE COMPOSITIONS FOR ORAL ABSORPTION
摘要 Instant invention is a flavor stable, pleasant tasting zinc acetate composition that shortens the duration of common colds in humans. The composition is used in the oral cavity of a human suffering from a common cold. The composition comprises highly ionizable zinc acetate and a pharmaceutically acceptable carrier such as fructose or sucrose with various additions. Compositions are unique in that they are pleasant tasting and do not have an offensive aftertaste, yet deliver zinc ions into saliva. Composition is thermally, chemically and flavor stable. The composition may be prepared in the form of a compressed tablet, lozenge, powder, liquid or chewing gum. Instant composition delivers strongly antirhinoviral zinc ions to the oral mucosa of a human. in vitro, zinc<+2> is as antirhinoviral and as protective of cell monolayers as interferon and is a potent interferon inducer. Said pleasant tasting composition is an improvement upon a slow-release candy composition comprising a hard candy base, zinc acetate and an amino acid; and said composition is an improvement upon a medicinal composition for release of zinc ion consisting essentially of a suitable pharmaceutical carrier, zinc acetate and anethole.
申请公布号 WO9210997(A1) 申请公布日期 1992.07.09
申请号 WO1991US09487 申请日期 1991.12.17
申请人 EBY, GEORGE, A., III 发明人 EBY, GEORGE, A., III
分类号 A61K9/00;A61K31/315 主分类号 A61K9/00
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