| 发明名称 |
Process for 3-exomethylenecepham sulfoxide esters. |
| 摘要 |
<p>3-Exomethylenecepham sulfoxide esters are obtained in improved yields via cyclization of 3-methyl-2-(4-chlorosulfinyl-2-oxo-3-amino-1-azetidinyl)-3-butenoic acid esters under anhydrous conditions with a Lewis acid-type Friedel-Crafts catalyst in the presence of a nitro compound, e.g., nitromethane, nitroethane, nitropropane or nitrobenzene.</p> |
| 申请公布号 |
EP0494118(A1) |
申请公布日期 |
1992.07.08 |
| 申请号 |
EP19920300054 |
申请日期 |
1992.01.03 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BROWN, FRANK, JR.;GINAH, FRANCIS ORERENYO;WINNEROSKI, LEONARD LARRY, JR. |
| 分类号 |
B01J27/135;C07B61/00;C07D501/00;C07D501/08;C07D501/14;C07D501/22 |
主分类号 |
B01J27/135 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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