发明名称 |
CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION |
摘要 |
<p>A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C12-C36 fatty alcohol and a polyalkylene gylcol. Preferably the first substance is a cyclodextrin, especially a beta-cyclodextrin, whilst the second substance is a C14-C22 fatty alcohol, especially stearyl alcohol, cetyl alcohol, cetostearyl alcohol or myristyl alcohol. The matrix may also contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose.</p> |
申请公布号 |
EP0251459(B1) |
申请公布日期 |
1992.07.08 |
申请号 |
EP19870304189 |
申请日期 |
1987.05.12 |
申请人 |
EUROCELTIQUE SA |
发明人 |
ELGER, GORDON ANTHONY;LESLIE, STEWART THOMAS;MALKOWSKA, SADRA THERESE ANTOINETTE;MILLER, RONALD BROWN;NEALE, PHILIP JOHN |
分类号 |
A61K47/10;A61K9/20;A61K9/22;A61K47/00;A61K47/08;A61K47/36;A61K47/40 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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