发明名称 Arylalkylamine derivatives
摘要 Disclosed is a novel arylalkylamine derivative represented by the formula (I) <IMAGE> (I) wherein X represents -O-, -CH2- or -NR3- in which R3 represents hydrogen or lower alkyl; Y represents -NH- or <IMAGE> Z represents <IMAGE> in which R4 represents hydrogen or lower alkyl or <IMAGE> Q represents an optionally substituted aryl or optionally substituted aromatic heterocyclic group; each of R1 and R2 independently represents hydrogen or lower alkyl; each of m and n independently represents an integer of 0 or 1; and a pharmaceutically acceptable salt thereof. The compound (I) and a pharmaceutically acceptable salt thereof show bronchodilatory and antiallergic activities, and are useful for treating respiratory disorders such as bronchial asthma.
申请公布号 US5128369(A) 申请公布日期 1992.07.07
申请号 US19910742074 申请日期 1991.08.07
申请人 KYOWA HAKKO KOGYO CO., LTD. 发明人 YAMATO, MASATOSHI;HASHIGAKI, KUNIKO;MANABE, HARUHIKO;OHMORI, KENJI
分类号 A61K31/35;A61K31/352;A61K31/47;A61K31/472;A61P11/08;A61P37/08;C07C215/28;C07C215/52;C07C215/60;C07C215/62;C07C217/48;C07C217/70;C07C217/72;C07C225/16;C07D213/38;C07D217/14;C07D311/76;C07D405/12;C07D407/12;C07D409/12 主分类号 A61K31/35
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