发明名称 |
Arylalkylamine derivatives |
摘要 |
Disclosed is a novel arylalkylamine derivative represented by the formula (I) <IMAGE> (I) wherein X represents -O-, -CH2- or -NR3- in which R3 represents hydrogen or lower alkyl; Y represents -NH- or <IMAGE> Z represents <IMAGE> in which R4 represents hydrogen or lower alkyl or <IMAGE> Q represents an optionally substituted aryl or optionally substituted aromatic heterocyclic group; each of R1 and R2 independently represents hydrogen or lower alkyl; each of m and n independently represents an integer of 0 or 1; and a pharmaceutically acceptable salt thereof. The compound (I) and a pharmaceutically acceptable salt thereof show bronchodilatory and antiallergic activities, and are useful for treating respiratory disorders such as bronchial asthma.
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申请公布号 |
US5128369(A) |
申请公布日期 |
1992.07.07 |
申请号 |
US19910742074 |
申请日期 |
1991.08.07 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
YAMATO, MASATOSHI;HASHIGAKI, KUNIKO;MANABE, HARUHIKO;OHMORI, KENJI |
分类号 |
A61K31/35;A61K31/352;A61K31/47;A61K31/472;A61P11/08;A61P37/08;C07C215/28;C07C215/52;C07C215/60;C07C215/62;C07C217/48;C07C217/70;C07C217/72;C07C225/16;C07D213/38;C07D217/14;C07D311/76;C07D405/12;C07D407/12;C07D409/12 |
主分类号 |
A61K31/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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