发明名称 NUEVOS LIGANDOS MACROCICLICOS NITRADOS, PROCEDIMIENTO DE PREPARACION, COMPLEJO POLIMETALICOS, COMPOSICION DE DIAGNOSTICO Y TERAPEUTICA.
摘要 Ligands of formula <IMAGE> in which B represents a group <IMAGE> W represents the group <IMAGE> in which x and Z represent a heterocycle. An additional subject of the invention is the mono- or polymetallic complexes formed by these ligands with metal ions chosen from lanthanide ions, transition metal ions, barium, bismuth, lead and the radioisotopes <99m>Tc, <111>In, <90>Y, <64>Cu and <169>Yb, as well as the physiologically acceptable salts of these complexes. The salts of these complexes can be used as diagnostic and therapeutic agents in magnetic resonance imaging, X-ray radiology, as in vivo chemical displacement agents and in nuclear medicine.
申请公布号 MX9200319(A) 申请公布日期 1992.07.01
申请号 MX19920000319 申请日期 1992.01.24
申请人 GUERBET S.A. 发明人 OLIVIER ROUSSEAUX;MICHEL SCHAEFER;ANNE BOUILLOT;DOMINIQUE MEYER
分类号 A61K49/00;A61K49/04;A61K51/00;A61K51/04;C07D;C07D401/06;C07D403/06;C07D405/04;C07D405/06;C07D493/04;C07F9/6558;(IPC1-7):A61K49/04 主分类号 A61K49/00
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