| 摘要 |
6-16608/+ Process for the preparation of optically active secondary amines Asymmetric hydrogenation of prochiral N-aliphatic ketimines to give optically active secondary amines at a temperature from -20 to 80.degree.C, a hydro-gen pressure of 105 to 107 Pa, with the addition of catalytic amounts of an iridium compound of the formula III or IIIa ¢XIrYZ! (III) or ¢XIrY!?A? (IIIa) in which X is two olefin ligands or a diene ligand, Y is a chiral diphosphine the secondary phosphine group of which are attached through 2-4 C atoms and which, together with the Ir atom, forms a 5-membered, 6-membered or 7-membered ring, or Y is a chiral diphosphinite the phosphinite groups of which are attached via 2 C atoms and which, together with the Ir atom, forms a 7-membered ring, Z is Cl, Br or I and A is the anion of an oxygen acid or complex acid, and, if appropriate, with the addition of an ammonium chloride, bromide or iodide or an alkali metal chloride, bromide or iodide. |
