Fiber-optic physiological probes

摘要

Fiber optic sensors suitable for monitoring physiological analyte concentrations are described. The sensors include analyte permeable matrices disposed in a light path defined by the axial core at one end of an optical fiber segment. The matrix contains an indicator molecule covalently linked to a polymer or admixed with the polymer. The indicator molecule may be an absorptive molecule or a luminescent molecule. pH, PCO2, and PO2 sensors are described and may be disposed together in substantially coterminal arrangement to make a multivariable probe.