发明名称 METHOD OF ENHANCING GROWTH IN PATIENTS USING COMBINATION THERAPY
摘要 A method is disclosed for enhancing growth of a mammal by administration of a combination of effective amounts of IGF-I and GH so as to enhance the growth of the mammal over the enhancement in growth achieved using either IGF-I or GH alone in an amount equal to that used for either IGF-I or GH, respectively, in the combination. Preferably, the mammal is a child, the IGF-I is native-sequence, mature human IGF-I or human brain IGF-I, and the GH is native-sequence, mature human GH with or without a terminal methionine. In another preferred embodiment, the mammal is a non-human animal of economic importance such as a cow or pig.
申请公布号 US5126324(A) 申请公布日期 1992.06.30
申请号 US19900535005 申请日期 1990.06.07
申请人 GENENTECH, INC. 发明人 CLARK, ROSS G.;CRONIN, MICHAEL J.
分类号 A61K38/27;A61K9/00;A61K31/00;A61K38/20;A61K38/30;A61K47/10;A61K47/12;A61K47/26;A61P5/00;A61P43/00 主分类号 A61K38/27
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