FOERFARANDE FOER FRAMSTAELLNING AV MAENSKLIG VAEVNADS-PLASMINOGENAKTIVATOR (TPA) MED HJAELP AV SACCHAROMYCES CEREVISIAE -JAEST OCH I FOERFARANDET ANVAENDA HYBRIDVEKTORER.

摘要

The invention relates to yeast hibrid vectors comprising a yeast promoter and a tissue plasminogen activator coding region which is controlled by said promoter, to yeast cells transformed with said hybrid vectors, to yeast cells containing a chromosomally integrated gene for tissue plasminogen activator, and to novel tissue plasminogen activators. The invention also provides processes for the production of said hybrid vectors, of said transformed yeast cells and of tissue plasminogen activators.