发明名称 |
3-(PIPERIDIN-1-YL)-CARBONYLMETHYL-ISOINDOLIN-1-ONE |
摘要 |
A compound of the formula wherein X is hydrogen, halogen or nitro; Ar is phenyl or naphthyridinyl which may optionally be substituted; and either one of Z1 and Z2 is hydrogen and the other is lower alkanoyloxy or hydroxy, each of Z1 and Z2 is lower alkoxy, or Z1 and Z2 combinedly represent hydroxyimino, oxo or a group of the formyla: in which Y is oxygen or sulfur and A is a branched or unbranched lower alkylene chain; and a salt thereof, act on the central nervous system but are weak in adverse effects such as hypnotic and muscle relaxant effects. |
申请公布号 |
CA1304381(C) |
申请公布日期 |
1992.06.30 |
申请号 |
CA19850490715 |
申请日期 |
1985.09.13 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
GOTO, GIICHI;SAJI, YOSHIAKI |
分类号 |
A61K31/4427;A61K31/445;A61P25/20;A61P25/24;A61P25/26;C07D209/46;C07D317/00;C07D401/06;C07D471/04;C07D491/10;C07D491/113;C07D519/00 |
主分类号 |
A61K31/4427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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