The RESA and FIRA antigens of plasmodium falciparum
摘要
DNA molecules comprising polynucleotide sequences substantially corresponding to all or a portion of the base sequence coding for an antigen of Plasmodium falciparum selected from the group consisting of the RESA antigen, the FIRA antigen, and other antigens of P. falciparum cross-reactive therewith. Such DNA molecules are capable of being expressed as polypeptide(s). Synthetic peptides or polypeptides displaying the antigenicity of all or a portion of the RESA or FIRA antigens of P. falciparum. Compositions for stimulating immune responses against P. falciparum antigens in a mammal, comprising at least one polypeptide displaying the antigenicity of the RESA or FIRA antigens of P. falciparum.
申请公布号
US5126264(A)
申请公布日期
1992.06.30
申请号
US19900554946
申请日期
1990.07.16
申请人
THE WALTER & ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人
KEMP, DAVID J.;ANDERS, ROBIN F.;COPPEL, ROSS;BROWN, GRAHAM V.;SAINT, ROBERT B.;COWMAN, ALAN E.;BIANCO, ALBERT E.;MITCHELL, GRAHAM F.