| 摘要 |
Title compds.(I; R1 = H or ethyl; R2 = methyl, ethyl or n-propyl; Y = H, methyl, methoxy, F, Cl), useful as an anti-inflammatory agent, were prepd. by the reaction of II (X = C1-8 alkoxy, C7-10 phenylalkoxy, phenyloxy, halogen, C1-8 alkylamino, anilino) and III at 20-200oC in organic solvent. Thus, 26.9 g methyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide and 2.5 g 2-amino-5-methyl-thiazole were refluxed for 24 hr in 4l xylene to give 26.0 g I.
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