Mammalian G protein-coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereto can be used to identify agonists and antagonists of G protein-coupled glutamate receptor mediated neuronal excitation and in methods of diagnosis.
申请公布号
WO9210583(A1)
申请公布日期
1992.06.25
申请号
WO1991US09422
申请日期
1991.12.12
申请人
ZYMOGENETICS, INC.;THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGT
