| 发明名称 |
AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
<p>The compounds of the formula <IMAGE> I wherein A, R1, R2, R3, R4, R5 and R6 are as set forth above, are described. The compounds of formula I have an inhibitory activity on the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations for the control or prevention of high blood pressure and cardiac insufficiency.</p> |
| 申请公布号 |
NZ228175(A) |
申请公布日期 |
1992.06.25 |
| 申请号 |
NZ19890228175 |
申请日期 |
1989.03.01 |
| 申请人 |
F HOFFMANN-LA ROCHE & CO AG |
发明人 |
BRANCA, QUIRICO;NEIDHART, WERNER;RAMUZ, HENRI;STADLER, HEINZ;WOSTL, WOLFGANG |
| 分类号 |
A61K31/16;A61K31/41;A61K31/425;A61K31/426;A61K31/44;A61K31/4427;A61K31/443;A61K38/00;A61P9/04;A61P9/12;C07C215/26;C07C231/02;C07C237/00;C07C237/22;C07C317/44;C07C323/60;C07D231/12;C07D233/54;C07D233/64;C07D263/04;C07D263/06;C07D263/24;C07D277/20;C07D277/30;C07D307/52;C07D333/24;C07D401/12;C07D405/06;C07D405/12;C07D413/12;C07D417/06;C07D417/12;C07F9/6506;C07K5/06;C07K14/81;(IPC1-7):C07D233/64;C07C317/28;A61K37/02;A61K31/535;A61K31/415;A61K31/38 |
主分类号 |
A61K31/16 |
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