发明名称 |
4-(4-OR 6-(TRIFLUOROMETHYL-2-PYRIDINYL))-1-PIPERAZINYL-ALKYL SUBSTITUTED LACTAMS |
摘要 |
The invention relates to neuroleptic/antidepressant 4-[4- or 6-(trifluoromethyl)-2-pyridinyl]-1-piperazinylalkyl substituted lactam derivatives having the general structure of formula I: <CHEM> wherein one of the groups R1 and R2 is CF3, and the other is hydrogen or CF3; R3 is hydrogen or (1-4 C) alkyl; n is an integer from 4 to 5; and m is an integer from 1 to 2; or pharmaceutically acceptable salts thereof. The invention also includes processes for making the compounds and their salts. |
申请公布号 |
ZA9108221(B) |
申请公布日期 |
1992.06.24 |
申请号 |
ZA19910008221 |
申请日期 |
1991.10.15 |
申请人 |
AKZO N.V. |
发明人 |
PATRICK CARLIER;MICHEL COMBOURIEU;CLAUDE POISSON;ANDRE JEAN-CLAUDE MONTEIL |
分类号 |
A61K31/44;A61K31/4427;A61P25/18;A61P25/24;A61P25/26;C07D401/12 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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