发明名称 PYRIMIDINE BIOSYNTHESIS INHIBITORS USEFUL AS IMMUNOSUPPRESSIVE AGENTS
摘要 The pyrimidine biosynthesis inhibitors dichloroallyl lawsone, N-(phosphonoacetyl)-L-aspartic acid (PALA), pyrazofurin, and derivatives thereof, are useful as immunomodulatory and anti-inflammatory agents. Pharmaceutical formulations containing these compounds are useful for the treatment of autoimmune diseases, chronic inflammatory diseases, and of organ transplantation rejections.
申请公布号 ZA9008745(B) 申请公布日期 1992.06.24
申请号 ZA19900008745 申请日期 1990.10.31
申请人 E.I. DU PONT DE NEMOURS AND COMPANY 发明人 NEIL RICHARD ACKERMAN;BRUCE DONALD JAFFEE
分类号 A61K31/12;A61K31/66;A61P29/00;A61P37/00;A61P37/06;G01N33/53 主分类号 A61K31/12
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