| 发明名称 |
SUBSTITUTED PYRAZINES, PYRIMIDINES AND PYRIDAZINES FOR USE IN THE TREATMENT OF GLAUCOMA |
| 摘要 |
T1091Y SUBSTITUTED PYRAZINES, PYRIMIDINES AND PYRIDAZINES FOR USE IN THE TREATMENT OF GLAUCOMA A class of pyrazine, pyrimidine and pyridazine derivatives, substituted by a non-aromatic azabicyclic ring system and optionally by up to two further substituents, is of use in the preparation of medicaments, especially formulations adapted for topical administration to the eye, suitable for the treatment of glaucoma and/or for reducing intraocular pressure.
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| 申请公布号 |
CA2058178(A1) |
申请公布日期 |
1992.06.22 |
| 申请号 |
CA19912058178 |
申请日期 |
1991.12.20 |
| 申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
LOTTI, VICTOR;SHOWELL, GRAHAM A. |
| 分类号 |
A61K31/40;A61K31/435;A61K31/495;A61K31/50;A61K31/505;A61K31/55;A61P27/02;A61P43/00;C07D453/02;C07D453/06;C07D471/08;C07D487/08;(IPC1-7):C07D453/00 |
主分类号 |
A61K31/40 |
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