NEW USE OF PEPTIDE DERIVATIVE

摘要

An antiinflammatory or gastrointestinal motility-modulating composition comprising a peptide derivative of the general formula : wherein R1 is hydrogen or an acyl group; R2 is hydroxy and R3 is carboxy or protected carboxy, or R2 and R3 are linked together to represent a group of the formula : ; R4 is hydroxy or protected hydroxy; R5 is hydroxy or protected hydroxy; R6 is hydroxy, protected hydroxy or lower alkoxy; and ??? is a single bond or a double bond, or a pharmaceutically acceptable salt thereof as an active ingredient, in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient. The use of the above peptide derivative or salt for the manufacture of a-medic-ament for preventing and/or treating inflammation or for modulating the gastrointestinal motility is also disclosed, as well as the above mentioned method of prevention and/or treatment.