| 发明名称 |
Pharmaceutical agents. |
| 摘要 |
<p>The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.</p> |
| 申请公布号 |
EP0490648(A1) |
申请公布日期 |
1992.06.17 |
| 申请号 |
EP19910311504 |
申请日期 |
1991.12.11 |
| 申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
TIMKO, ROBERT JOSEPH;CLEMENTS, ARLENE;BRADWAY, RANDY JOHN;HOLOHAN, JAMES JOSEPH;EDWARDS, IEUAN JOHN |
| 分类号 |
A61K9/20;A61K31/18;A61K9/00;A61K9/16;A61K31/166;A61K31/40;A61K31/403;A61K31/404;A61K47/26;A61K47/32;A61K47/38;A61P9/00;A61P11/00;A61P11/06;A61P17/00;A61P29/00;A61P35/00;A61P37/08;C07C307/02;C07D209/10;C07D209/18;C07D209/24;C07D209/30;C07D209/40 |
主分类号 |
A61K9/20 |
| 代理机构 |
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