发明名称 |
MEASLES VIRUS RECOMBINANT POXVIRUS VACCINE |
摘要 |
Recombinant poxvirus (I) contg. DNA from Morbilli-virus in a nonessential region of the poxvirus genome is new. Also described are: (1) a vaccine for inducing an immunological response in a host animal inoculated with the vaccine, the vaccine comprising a carrier and (I); and (2) a method for protecting a dog against canine distemper, which comprises inoculating the dog. with (I). In (I) the Morbillivirus is the measles virus and the DNA codes for measles virus haemagglutinin glycoprotein and/or measles virus fusion protein. DNA is expressed in host by the prodn. of a measles virus glycoprotein. Poxvirus is a vaccinia, avipox or canarypox virus and contains a promoter for expressing the Morbillivurs DNA. |
申请公布号 |
AU1253892(A) |
申请公布日期 |
1992.06.11 |
申请号 |
AU19920012538 |
申请日期 |
1991.11.20 |
申请人 |
VIROGENETICS CORPORATION |
发明人 |
ENZO PAOLETTI;JILL TAYLOR |
分类号 |
A61K39/275;A61K35/76;A61K39/00;A61K39/165;A61K39/175;A61K39/265;A61P31/12;A61P31/14;C07K14/12;C12N7/00;C12N7/01;C12N15/09;C12N15/39;C12N15/86;C12N15/863;C12N15/87 |
主分类号 |
A61K39/275 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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