| 发明名称 |
LABELLED, MODIFIED OLIGONUCLEOTIDES |
| 摘要 |
The invention relates to novel labelled modified oligonucleotides useful for gene therapy, a conjugate of a targeting moiety, such as an antibody and a modified oligonucleotide complementary to the labelled oligonucleotide, the combination of both being useful in therapy of viral infections, tumours and (auto) immunodiseases. Also disclosed are pharmaceutical formalations comprising the various compounds.
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| 申请公布号 |
CA2057292(A1) |
申请公布日期 |
1992.06.11 |
| 申请号 |
CA19912057292 |
申请日期 |
1991.12.09 |
| 申请人 |
AKZO N.V. |
发明人 |
KUIJPERS, WILHELMUS H. A.;KASPERSEN, FRANCISCUS M.;VAN BOECKEL, CONSTANT A. A. |
| 分类号 |
A61K31/70;A61K31/7088;A61K31/7105;A61K31/713;A61K39/395;A61K39/44;A61K47/48;A61K51/00;A61K51/04;A61K51/10;A61P31/12;A61P35/00;A61P37/00;C07H21/00;C07H21/04;(IPC1-7):C07H21/00;A61K48/00 |
主分类号 |
A61K31/70 |
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