TOPICAL COMPOSITIONS FOR TRANSDERMAL DELIVERY OF PRODUG DERIVATIVES OF MORPHINE

摘要

The invention relates to topical composition for transdermal delivery of morphine. The composition comprises an effective amount of a morphine ester in association with a topical pharmaceutical carrier which gives solutions, suspensions, ointments, lotions, creams, gels, pastes, jellies, sprays and aerosols and/or together with a medical device. The invention also relates to the use of the morphine esters for the manufacture of a topical medicament for transdermal delivery for relieving pain or tranquilizing a mammal.