发明名称 |
ACETAMIDE DERIVATIVES |
摘要 |
The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives. |
申请公布号 |
ZA9105783(B) |
申请公布日期 |
1992.05.27 |
申请号 |
ZA19910005783 |
申请日期 |
1991.07.23 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC. |
发明人 |
DAVID ROBERT BRITTAIN;STEVEN PAUL BROWN;ANTHONY LOREN COOPER;JETHRO LAWRENCE LONGRIDGE;JEFFREY JAMES MORRIS;JOHN PRESTON;LINDA SLATER |
分类号 |
A61K31/255;A61K31/00;A61K31/04;A61K31/10;A61K31/16;A61P3/00;A61P3/08;A61P3/10;A61P5/00;A61P25/02;A61P27/00;A61P43/00;C07C313/04;C07C315/00;C07C315/02;C07C317/14;C07C317/40;C07C323/41 |
主分类号 |
A61K31/255 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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