LABELLED VITAMIN D3 DERIVATIVE AND PRODUCTION PROCESS THEREOF

摘要

The present invention discloses a novel, labelled vitamin D3 derivative in which hydrogen atoms on the skeleton portion, i.e. 6- and 19-positions, are substituted with a deuterium atom or a tritium atom, as well as a novel production process of the labelled vitamin D3 derivative carried out by way of sulfur dioxide addition reaction of a vitamin D3 derivative. The labelled portion of the novel vitamin D3 is resistant against in vivo metabolism and make a long period tracing of its pharmacodynamics in a living body possible.