发明名称 POLYPEPTIDE WITH KD HMFG DIFFERENTIATION ANTIGEN BINDING SPECIFICITY
摘要 A polypeptide has the antibody binding activity of the 46K dalton HMFG differentiation antigen and/or homology to at least one of the light chains of clotting factors V and VIII and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for the polypeptide of the invention or a functional fragment thereof. in vivo and in vitro methods for therapy vaccination and detecting the presence of the polypeptide, the antibody, the DNA and RNA of the invention are provided. DNA and RNA sequences encode the polypeptide of the invention or fragments thereof and immunoassay kits comprise the antibodies and/or polypeptides of the invention.
申请公布号 AU9057091(A) 申请公布日期 1992.05.26
申请号 AU19910090570 申请日期 1991.09.16
申请人 JOHN MUIR CANCER & RESEARCH INSTITUTE 发明人 ROBERTO L. CERIANI;JERRY ARTHUR PETERSON;DAVID JAMES LAROCCA
分类号 A61K31/70;A61K38/00;A61K39/00;A61K39/395;A61K47/48;A61K48/00;A61K49/00;A61K51/10;A61P35/00;A61P37/02;C07K14/435;C07K14/47;C07K14/705;C07K14/745;C07K14/755;C07K16/00;C07K16/18;C07K16/30;C07K19/00;C12N15/02;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/53;G01N33/574;G01N33/577 主分类号 A61K31/70
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