发明名称 |
POLYPEPTIDE WITH KD HMFG DIFFERENTIATION ANTIGEN BINDING SPECIFICITY |
摘要 |
A polypeptide has the antibody binding activity of the 46K dalton HMFG differentiation antigen and/or homology to at least one of the light chains of clotting factors V and VIII and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for the polypeptide of the invention or a functional fragment thereof. in vivo and in vitro methods for therapy vaccination and detecting the presence of the polypeptide, the antibody, the DNA and RNA of the invention are provided. DNA and RNA sequences encode the polypeptide of the invention or fragments thereof and immunoassay kits comprise the antibodies and/or polypeptides of the invention. |
申请公布号 |
AU9057091(A) |
申请公布日期 |
1992.05.26 |
申请号 |
AU19910090570 |
申请日期 |
1991.09.16 |
申请人 |
JOHN MUIR CANCER & RESEARCH INSTITUTE |
发明人 |
ROBERTO L. CERIANI;JERRY ARTHUR PETERSON;DAVID JAMES LAROCCA |
分类号 |
A61K31/70;A61K38/00;A61K39/00;A61K39/395;A61K47/48;A61K48/00;A61K49/00;A61K51/10;A61P35/00;A61P37/02;C07K14/435;C07K14/47;C07K14/705;C07K14/745;C07K14/755;C07K16/00;C07K16/18;C07K16/30;C07K19/00;C12N15/02;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/53;G01N33/574;G01N33/577 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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