发明名称 Antiinflammatory leukotriene B4 analogs
摘要 PCT No. PCT/US87/03364 Sec. 371 Date Jun. 29, 1989 Sec. 102(e) Date Jun. 29, 1989 PCT Filed Dec. 22, 1987 PCT Pub. No. WO88/05045 PCT Pub. Date Jul. 14, 1988.This invention encompasses novel analogs of Leukotriene B4 which are selected from a compound of formula I, B-C APPROX C-CH2C(M2)-C APPROX C-Y-C(M1)-A, or formula II, B-C APPROX C-CH2C(M2)-C APPROX C-P-R5-A: wherein Y is: <IMAGE> <IMAGE> wherein P is: <IMAGE> <IMAGE> <IMAGE> Patentable intermediates, process for making the novel analogs and intermediates and preparation of useful pharmacological agents comprising the analogs and intermediates are part of this invention.
申请公布号 US5116981(A) 申请公布日期 1992.05.26
申请号 US19890438491 申请日期 1989.06.29
申请人 THE UPJOHN COMPANY 发明人 MORRIS, JOEL
分类号 C07C33/28;C07C33/30;C07C59/48;C07D213/30;C07D213/55;C07D213/89;C07D303/40;C07D307/42;C07D307/54;C07D309/30;C07D405/06;C07K5/06 主分类号 C07C33/28
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