A superfusion apparatus for the controlled reaction of a sample within a test chamber through controlled exposure to a series of reagents in a set test sequence is provided for electrical or chemical stimulation to determine if a receptor binding compound is an agonist or antagonist. The superfusion apparatus provides a mass production but meticulously controlled sample environment for controlling temperature, quantity and arrangement of reagents and wash fluids to provide a high reproducability of results which may be compuer assisted. The device has a fully automated mode or a manually operated mode. The fully automated mode allows for the storage and execution of a number of different tests to be performed on the samples due to the provision of desired sequences of test parameters.
申请公布号
US5114681(A)
申请公布日期
1992.05.19
申请号
US19900491717
申请日期
1990.03.09
申请人
BIOMEDICAL RESEARCH AND DEVELOPMENT LABORATORIES, INC.
发明人
BERTONCINI, JOSEPH;KROENER, CALVIN;COBB, WAYNE;EVANS, ROBERT