PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES

摘要

PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used. A 3999-67/MR