发明名称 |
PROCESS FOR THE PRODUCTION OF PERMANENTLY CULTURABLE ANIMAL AND HUMAN CELL LINES AND THE USE THEREOF |
摘要 |
A method for obtaining permanently culturable human and animal cell lines, as well as uses for these cell lines, are disclosed. The method involves fusing cells of a non-immortal cell line with cytoplasts or cytoplasma fractions of "immortal", transformed cells such as immortal myeloma cells, ascites-tumor cells or Epstein Barr Virus infected cells. Once fusion takes place the product is a permanently culturable variant of the previously normal cell line.
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申请公布号 |
US5114847(A) |
申请公布日期 |
1992.05.19 |
申请号 |
US19900590602 |
申请日期 |
1990.09.25 |
申请人 |
BOEHRINGER MANNHEIM GMBH |
发明人 |
JUNGFER, HERBERT;BARCHET, HEINRICH;ALBERT, WINFRIED |
分类号 |
G01N33/577;A61K35/12;A61K38/16;A61K39/395;C07K14/00;C07K14/52;C07K16/00;C12N15/00;C12N15/02;C12P21/08;C12R1/91;G01N33/48 |
主分类号 |
G01N33/577 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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