| 摘要 |
Novel 9-amino-1,2,3,4-tetrahydroacridines and related compounds of the formula <IMAGE> wherein R1 is H, loweralkyl, or benzyl; R3 is H, loweralkyl, a group of the formula CH2CHR2Hal wherein R2 is hydrogen, loweralkyl, or phenyl and Hal is chloro, bromo, or iodo, or a group of the formula CHR2CO2R5 wherein R2 is as above and R5 is H or loweralkyl; Z is O or S; X is H, halogen, loweralkoxy, loweralkyl, or trifluoromethyl; n is 1, 2, or 3; the group ZR3 is bound to either the A- or B-position of the heteroaromatic nucleus; the pharmaceutically acceptable salts thereof; and the optical isomers thereof, useful as intermediates for the preparation of memory dysfunction relieving hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines are related compounds and for relieving memory dysfunction are disclosed.
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