摘要 |
1,260,969. Guanidine derivatives. SANDOZ Ltd. 28 Jan., 1970 [7 Feb., 1969], No. 4029/70. Heading C2C. The invention comprises compounds of formula and their acid addition salts, wherein X 1 and X 2 are each Cl, Br or I, and a process for making them by reacting guanidine with C 1-6 alkyl esters of the corresponding bis(p-halophenoxy)acetic acid. Therapeutic compositions for oral or parenteral administration comprise compounds of the above formula, which have hypocholesteremic/ hypolipemic activity. |