| 摘要 |
1278758 Nitroimidazole derivatives RHONEPOULENC SA 19 April 1971 [16 Feb 1970] 21741/71 Heading C2C Nitroimidazole derivatives of Formula I (in which R 1 is C 1-6 alkyl and R 2 is C 1-4 alkyl) are prepared by reduction of ketones of Formula II Ketones of Formula II are prepared by nitrating a compound of Formula III During the nitration, 4-nitro and 5-nitro derivatives of the imidazole are formed and these are separated by usual methods. Compounds of Formula III are prepared by reacting a 2-C 1-4 alkyl-imidazole with a halomethyl C 1-6 alkyl ketone. |
