(I) X = H or (1-3C) alkyl Y = Ph or (7-9C) aralkyl, opt. subst. in the ring, by 1 or 2 halogen, or by p-NO2 or p-CF3. Z = CR'R2R3, where R' and R2

摘要

(I) X = H or (1-3C) alkyl - Y = Ph or (7-9C) aralkyl, opt. subst. in the ring, by 1 or 2 halogen, or by p-NO2 or p-CF3. - Z = CR'R2R3, where R' and R2 = H or (1-4C) alkyl, and R3 = CN, CO2R4, or CONHR5, - R4 = (1-5C) alkyl opt. subst. by OH,(is not > 8C) dialkylaminoalkyl, (is not >9C) aralkyl, or aryl. - and R5 = H, NH2 (is not > 8C) dialkylaminoalkyl, (is not > 5C) alkoxycarbonylalkyl, or (is not >3C) carboxyalkyl. - (II) Salts of (I). - Anti-inflammatories, analgesics, and anti-pyretics which are also active in lowering the blood fibrinogen, cholesterol, and/or triglyceride contents.