| 摘要 |
This invention relates to a new preparation process of the 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)- 7 hydroxy-furo - (3,4-c) - pyridine derivatives of the general formula : wherein, each of Al and A2 independently, represents various substituents consisting in reacting a 6-formyl-7-hydroxy-furo-(3,4-c)-pyridine derivative of the general formula : wherein Al and A2 have the above meanings with a slight excess of l-dimethylaminomethyl-vinylmagnesium bromide at the boil, in a non polar solvent such as tetrahydrofuran. |
