摘要 |
Industrial procedure for obtaining a derived hydrazine with the chemical name L - α - hydrazine - 3,4 - dihydroxy - α - methylbenzene - propanoic monohydrate, characterized by comprising the following operational phases: By the reaction of the hydrochloride of L - α - amino - 3,4 - dimethoxy - α - methylbenzenepropionitryl with concentrated HCl at 80- 90 degree C, the corresponding acid is obtained, which is treated at 50-60 degree C in an aqueous medium with potassium cyanate in order to obtain L - α - (3,4 - dimethoxybenzyl) - α - methylhydantoic acid, which is subsequently reacted with sodium hypochlorite in an alkaline aqueous medium at 0 degree C, giving the corresponding derived hydrazine which, by treatment with hydrobromic acid at a concentration of 40-62% and at 100-120 degree C, gives rise to the product desired. It is applied in the treatment of Parkinson's disease. <IMAGE>
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