发明名称 |
Preparation of novel invermectin compounds. |
摘要 |
<p>Incubation of 13- beta -hydroxy avermectin aglycone with a species of B. subtilis results in the production of 13- beta ivermectin monoglucopyranoside as the major product and of 5- beta ivermectin monoglucopyranoside as the minor product.</p> |
申请公布号 |
EP0482795(A1) |
申请公布日期 |
1992.04.29 |
申请号 |
EP19910309296 |
申请日期 |
1991.10.09 |
申请人 |
MERCK & CO. INC. |
发明人 |
INAMINE, EDWARD S.;CHEN, SHIEH-SHUNG TOM;PETUCH, BRAIN R.;ARISON, BYRON H. |
分类号 |
C07H17/08;A61K31/70;A61K31/7042;A61K31/7048;A61P33/00;C07H19/01;C12P17/18;C12P19/62;C12R1/125 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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