| 摘要 |
Derivatives of general formula (I): …<IMAGE>… in which:… R1 represents a hydrogen atom or a lower alkyl group,… A represents a hydrogen atom, and in this case B represents a group CO-G, G being:… - either a heteroaryl group chosen from furan, indole, pyrrole, pyridine, quinoline, isoquinoline and benzofuran, optionally substituted with one or more lower alkyl or lower alkoxy groups or halogen atom,… - or a linear or branched lower alkyl group substituted with a carboxyl group,… - or a linear or branched lower alkenyl group substituted with a carboxyl group,… - or a phenyl or naphthyl group substituted with a carboxyl group,… or alternatively A forms with B a group CO(CH2)nCH(CH3) with n an integer equal to 1, 2, 3 or 4, the CO group being bound to the aromatic ring of the benzoxazolinone at position 5 or 6, as well as, where appropriate, their isomers and, when the compound of formula (I) possesses a carboxylic acid group, their addition salts with a pharmaceutically acceptable base, and when the compound of formula (I) contains a basic group, their addition salts with a pharmaceutically acceptable acid, on the understanding that lower alkyl and lower alkenyl mean linear or branched groups comprising from 1 to 6 carbon atoms. …<??>Medicaments. |
